CopiOs® Pericardium Membrane
Resorbable Barrier Membranes

Strong Meets Supple
Barrier Membrane Made From Bovine Pericardium
CopiOs Pericardium Membrane is a long-lasting, conformable barrier—strong enough to meet most clinical needs and supple enough to adapt to challenging graft contours. 1-4
- Demonstrated Performance
- Long-Lasting
- Retains Natural Tissue Structure
ZimVie is #2 in the Global Biomaterials Market
CopiOs Pericardium Membrane Features & Benefits

Demonstrated Performance
Clinically demonstrated performance in guided bone regeneration procedures,1, 2 where ease of manipulation and adaptability to surface contours is essential.
Long-Lasting
Shown to provide a stable, long-lasting barrier during healing and integration of Puros® Allografts and staged or immediately placed implants33,34
Retains Natural Tissue Structure
Supports an aesthetic soft tissue response1, 2 through facilitation of cell attachment and proliferation and remodeling into vascularized connective tissue.1, 3
Retains the structure and composition of natural tissue due to the proprietary Tutoplast process,, leading to optimal performance and handling.1, 2
Puros Allograft Block Unique Tutoplast Process
In 1969 the Tutoplast Tissue Sterilization Process was developed to sterilize and preserve tissue for implantation. More than 11 million implants have been sterilized through the Tutoplast Process with zero confirmed incidence of implant-associated infection.17
The Benefits of the Multi-Step Tutoplast Process
For allograft bone grafts, the process preserves the valuable bone mineral, collagen matrix, and tissue integrity 18 while inactivating pathogens and gently removing unwanted materials, such as cells, antigens, and viruses 17 – resulting in predictable, reliable, sterile, and safe tissue.17

*Images depict dermal processing
A Case Book
Clinical Cases for Regenerative Materials
- Ridge Augmentation Using Allogenic Bone Blocks
- Ridge Augmentation Using Customized Allogenic Bone Blocks
- Socket & Ridge Preservation
- Treatments Using Particulate Bone Graft Substitute
- Augmentation of Facial Dehiscences on Implant Surfaces with Puros Allograft Particles
- Maxillary Sinus Floor Augmentation
- Regeneration Of Peri-Implant Defects
- Ridge Augmentation Using Allogenic Bone Blocks
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